Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 known ✓ | P29475 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9478396 | 1.00 | CYP3A4 (0.63) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Acetic Acid SCHEMBL11077567 | 1.00 | CYP3A4 (0.63) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Acetic Acid SCHEMBL27359884 | 0.91 | CYP3A4 (0.52) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Butanedione SCHEMBL22686820 | 0.90 | CYP3A4 (0.63) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Bicarbonate SCHEMBL10433487 | 0.89 | CYP3A4 (0.71) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Carbamic Acid SCHEMBL28259977 | 0.86 | CYP3A4 (0.67) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| 3-Chloroaniline SCHEMBL7834114 | 0.84 | ALDH1A1 (0.71) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Acetic Acid SCHEMBL5550681 | 0.84 | ALDH1A1 (0.48) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Bicarbonate SCHEMBL27506301 | 0.84 | CYP3A4 (0.63) | CYP3A4CASP1RECQLALDH1A1PBRM1 | |
| Urea SCHEMBL28858286 | 0.83 | CYP3A4 (0.71) | CYP3A4CASP1RECQLALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945496-B1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | XEROX CORP (US) | 2003-11-12 | — | — | EP | claimed |
| CN-119390972-A | Antibacterial copolyamide and preparation method thereof | 华峰集团有限公司 | 2025-02-07 | — | — | CN | disclosed |