SCHEMBL711898

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL714288	0.94	TSHR (0.41)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL713746	0.84	TSHR (0.44)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL712203	0.84	TSHR (0.44)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL713523	0.81	TSHR (0.52)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL712254	0.78	TSHR (0.48)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL29579821	0.76	LMNA (0.48)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL23819499	0.75	TAAR1 (0.47)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL11633230	0.74	TAAR1 (0.46)	TSHRTAAR1LMNABCHEACHE
	SCHEMBL306297	0.72	LMNA (0.57)	TSHRTAAR1LMNADRD1MEN1
	SCHEMBL715660	0.72	LMNA (0.57)	TSHRTAAR1LMNADRD1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.