Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.59 |
| ▸ | CTSL | P07711 | 11/20 | 0.59 |
| ▸ | CTSS | P25774 | 11/20 | 0.59 |
| ▸ | CTSB | P07858 | 10/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714929 | 0.85 | CTSK (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6184189 | 0.84 | TACR2 (0.55) | CTSKCTSLCTSSCTSBSMN1; SMN2 | |
| SCHEMBL4716448 | 0.79 | CTSK (0.67) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6181617 | 0.79 | SMN1; SMN2 (0.56) | CTSKCTSLCTSSCTSBSMN1; SMN2 | |
| SCHEMBL4712545 | 0.77 | CTSK (0.82) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4716413 | 0.77 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4715515 | 0.76 | CTSK (0.69) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6184194 | 0.75 | EPHX2 (0.51) | CTSBSMN1; SMN2MAPTTACR2HTR2A | |
| SCHEMBL4712035 | 0.74 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4713424 | 0.74 | CTSK (0.89) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525036-B2 | Treating post-menopausal osteoporosis. | MERCK & CO., INC. | 2003-02-25 | — | — | US | disclosed |