SCHEMBL711939

SCHEMBL711939

CN(Cc1nc2ccccc2[nH]1)Cc1nc2ccccc2[nH]1

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
BCHE P06276 1/20 0.69
DDAH1 O94760 1/20 0.65
POLB P06746 1/20 0.59
PKM P14618 1/20 0.57
GAA P10253 1/20 0.56
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.51
TP53 P04637 1/20 0.51
TSHR P16473 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
PDE10A Q9Y233 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL709918 0.96 TDP1 (0.67) TDP1BCHEDDAH1POLBPKM
Hydrochloric Acid SCHEMBL708641 0.96 TDP1 (0.67) TDP1BCHEDDAH1POLBPKM
Hydrochloric Acid SCHEMBL709917 0.96 TDP1 (0.71) TDP1BCHEDDAH1POLBPKM
Hydrochloric Acid SCHEMBL708640 0.96 TDP1 (0.71) TDP1BCHEDDAH1POLBPKM
SCHEMBL708642 0.93 TDP1 (0.63) TDP1BCHEDDAH1POLBPKM
SCHEMBL23303404 0.93 BCHE (0.70) TDP1BCHEDDAH1POLBPKM
SCHEMBL23336458 0.90 BCHE (0.66) TDP1BCHEDDAH1POLBPKM
SCHEMBL4118942 0.89 BCHE (0.69) TDP1BCHEDDAH1POLBPKM
SCHEMBL1333203 0.87 BCHE (0.82) TDP1BCHEDDAH1POLBPKM
SCHEMBL7339555 0.86 TDP1 (0.63) TDP1BCHEDDAH1POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910426-B1 DIENE POLYMERISATION INEOS SALES (UK) LTD (GB) 2018-01-03 EP disclosed
EP-1603957-B1 POLYMERISATION AND OLIGOMERISATION CATALYSTS INEOS SALES UK LTD (GB) 2015-10-28 EP disclosed
EP-1603957-B1 POLYMERISATION AND OLIGOMERISATION CATALYSTS INEOS SALES UK LTD (GB) 2015-10-28 EP disclosed
EP-1789459-B1 POLYOLEFINS INEOS SALES UK LTD (GB) 2014-04-30 EP disclosed
EP-1789459-B1 POLYOLEFINS INEOS SALES UK LTD (GB) 2014-04-30 EP disclosed
US-8648000-B2 Diene polymerisation INEOS COMMERCIAL SERVICES UK LIMITED (GB) 2014-02-11 US disclosed
WO-2012035546-A3 A TAMPER EVIDENT MULTIPLE METALLIZED AND DEMETALLIZED SECURITY DEVICE AND PROCESS FOR PREPARING THE SAME KAPOOR AJAY (IN) 2012-05-10 WO disclosed
US-8124698-B2 Diene polymerisation INEOS EUROPE LIMITED (GB) 2012-02-28 US disclosed
EP-1918312-B1 Diene polymerisation INEOS COMMERCIAL SERVICES UK (GB) 2011-12-07 EP disclosed
US-7989565-B2 Polyolefins INEOS EUROPE LIMITED (GB) 2011-08-02 US disclosed
WO-2006048634-A1 POLYMERISATION CATALYSTS INEOS EUROPE LIMITED (GB) 2006-05-11 WO disclosed
US-20060094588-A1 Polymerisation and oligomerisation catalysts BARCLAYS BANK PLC (GB) 2006-05-04 US disclosed
EP-1603957-A1 POLYMERISATION AND OLIGOMERISATION CATALYSTS Innovene Europe Limited (GB) 2005-12-14 EP disclosed
WO-2005111099-A1 ETHYLENE COPOLYMERS INEOS EUROPE LIMITED (GB) 2005-11-24 WO disclosed
EP-1506277-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2005-02-16 EP disclosed
WO-2004083263-A1 POLYMERISATION AND OLIGOMERISATION CATALYSTS INNOVENE EUROPE LIMITED (GB) 2004-09-30 WO disclosed
WO-2003097780-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2003-11-27 WO disclosed
EP-1341893-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2003-09-10 EP disclosed
WO-2002048307-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2002-06-20 WO disclosed
EP-0218753-A1 Image-recieving element for the silver salt diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1987-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094588-A1 Polymerisation and oligomerisation catalysts CCNA1, AP2M1, AP2A1 TDP1 3905/4885BCHE 4523/4885DDAH1 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.