SCHEMBL711949

SCHEMBL711949

CC1(C)CC(CCCCNc2nc(Cl)nc(NCCCCC3CC(C)(C)NC(C)(C)C3)n2)CC(C)(C)N1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.33
NR1I2 O75469 1/20 0.33
AHR P35869 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 1/20 0.32
CHRM1 P11229 1/20 0.31
PDE4A P27815 1/20 0.31
PKM P14618 1/20 0.31
RAD52 P43351 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10814703 0.99 KMT2A (0.46) KMT2ALMNATSHRNR1I2AHR
SCHEMBL10811647 0.99 KMT2A (0.46) KMT2ALMNATSHRNR1I2AHR
SCHEMBL11236048 0.99 KMT2A (0.46) KMT2ALMNATSHRNR1I2AHR
SCHEMBL3145074 0.99 KMT2A (0.46) KMT2ALMNATSHRNR1I2AHR
SCHEMBL692463 0.97 KMT2A (0.40) KMT2ALMNATSHRNR1I2AHR
SCHEMBL11031867 0.96 KMT2A (0.43) KMT2ALMNATSHRNR1I2AHR
SCHEMBL10910241 0.96 KMT2A (0.43) KMT2ALMNATSHRNR1I2AHR
SCHEMBL10912242 0.96 KMT2A (0.43) KMT2ALMNATSHRNR1I2AHR
SCHEMBL11168811 0.93 TSHR (0.36) KMT2ALMNATSHR
SCHEMBL9367808 0.91 TSHR (0.36) KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4225974-A None JP disclosed
US-8830811-B2 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2014-09-09 US disclosed
EP-1878769-B1 RESIN COMPOSITION AND OPTICAL COMPONENT MITSUI CHEMICALS INC (JP) 2013-04-17 EP disclosed
US-8354529-B2 Polyamine derivative and polyol derivative BASF SE (DE) 2013-01-15 US disclosed
EP-2511274-A2 Polyamine derivative BASF SE (DE) 2012-10-17 EP disclosed
EP-2484677-A1 Polyamine derivative BASF SE (DE) 2012-08-08 EP disclosed
US-20120053270-A1 POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE MITA NARUYOSHI (JP) 2012-03-01 US disclosed
US-8076478-B2 Stabilizer; photostability, heat resistance, ozone resistance, oxidation resistance, electromagnetic resistance BASF SE (DE) 2011-12-13 US disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
US-20090310471-A1 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2009-12-17 US disclosed
EP-0107615-A1 Polyolefins stabilized by bis or tris (polyalkylpiperidinyl-amino) 1,3,5-triazines CIBA-GEIGY AG (CH) 1984-05-02 EP disclosed
EP-0101411-A2 Process for the chemical bond between a stabilising compound and a polymer CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed
EP-0075849-A2 Triazinyllactames, process for their preparation, their use as stabilisators for synthetic organic polymers and polymers stabilised by them HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-06 EP disclosed
EP-0002005-B1 PROCESS FOR BLOCKING END GROUPS OF POLYMERIC POLYALKYLPIPERIDINE DERIVATIVES, THE PRODUCTS WITH BLOCKED END GROUPS THUS OBTAINED AND THEIR USE AS LIGHT STABILISERS FOR SYNTHETIC MATERIALS CIBA-GEIGY AG (CH) 1983-01-19 EP disclosed
US-4322337-A PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1982-03-30 US disclosed
EP-0042554-A1 Polytriazinyl amines, process for their preparation, their use as stabilizing agents for synthetic polymers and polymers stabilized with these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-30 EP disclosed
EP-0014683-B1 POLYALKYLPIPERIDINE DERIVATIVES OF S-TRIAZINES, THEIR USE AS STABILIZERS FOR POLYMERS AND POLYMER COMPOSITIONS STABILIZED WITH THESE COMPOUNDS CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed
US-4288593-A PHOTOSTABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-4234707-A Polymeric light stabilizers for plastics CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
EP-0014683-A1 Polyalkylpiperidine derivatives of s-triazines, their use as stabilizers for polymers and polymer compositions stabilized with these compounds CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 KMT2A 736/4885LMNA 2153/4885TSHR 3969/4885
US-20120053270-A1 POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE H1-0, H1-3, NPM1 KMT2A 1254/4885LMNA 315/4885TSHR 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.