Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115662 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL4225962 | 0.85 | HTT (0.45) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL7122764 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL3939778 | 0.80 | DPP4 (0.47) | ALDH1A1KDM4EHTTHPGDKMT2A | |
| SCHEMBL6819044 | 0.78 | HTT (0.54) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL3938948 | 0.74 | HTT (0.48) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL15426075 | 0.74 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL15426087 | 0.74 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL4233824 | 0.73 | HTT (0.44) | ALDH1A1KDM4EHTTHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL3937144 | 0.72 | HTT (0.45) | ALDH1A1KDM4EHSD17B10HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | ALDH1A1 3164/4885KDM4E 1667/4885HSD17B10 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.