Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CD44 | P16070 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409314 | 0.93 | POLB (0.61) | POLBCD44TSHRCASP1NOS3 | |
| Hydrochloric Acid SCHEMBL8125648 | 0.89 | POLB (0.58) | POLBCD44TSHRCASP1NOS3 | |
| SCHEMBL4968725 | 0.82 | PDE10A (0.54) | POLBCD44TSHRCASP1NOS3 | |
| SCHEMBL31634585 | 0.82 | PDE10A (0.54) | POLBCD44TSHRCASP1NOS3 | |
| SCHEMBL2056779 | 0.80 | CD44 (0.57) | POLBCD44TSHRCASP1NOS3 | |
| SCHEMBL30565815 | 0.80 | CD44 (0.57) | POLBCD44TSHRCASP1NOS3 | |
| Hydrochloric Acid SCHEMBL3725463 | 0.78 | CD44 (0.55) | POLBCD44TSHRCASP1NOS3 | |
| Hydrochloric Acid SCHEMBL28212724 | 0.78 | CD44 (0.55) | POLBCD44TSHRCASP1NOS3 | |
| SCHEMBL3359993 | 0.78 | POLB (0.48) | POLBCD44TSHRCASP1NOS3 | |
| SCHEMBL30662151 | 0.76 | ALDH1A1 (0.58) | POLBCD44TSHRCASP1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660062-B2 | Contacting polyimide layer with a polyamine | INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING (SG) | 2003-12-09 | — | — | US | disclosed |
| US-20030070545-A1 | Chemical modification of polyimides | INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING (SG) | 2003-04-17 | — | — | US | disclosed |