Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.55 |
| ▸ | PTPRA | P18433 | 7/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249802 | 0.73 | BCHE (0.54) | BCHE | |
| SCHEMBL3143813 | 0.73 | BCHE (0.54) | BCHE | |
| SCHEMBL249801 | 0.73 | BCHE (0.54) | BCHE | |
| SCHEMBL3259775 | 0.73 | MME (0.57) | BCHE | |
| SCHEMBL3259764 | 0.73 | MME (0.57) | BCHE | |
| SCHEMBL17626995 | 0.72 | FAAH (0.55) | BCHE | |
| SCHEMBL3953856 | 0.72 | FAAH (0.55) | BCHE | |
| SCHEMBL21585496 | 0.72 | FAAH (0.55) | BCHE | |
| SCHEMBL6702717 | 0.72 | FAAH (0.55) | BCHE | |
| SCHEMBL30918986 | 0.72 | FAAH (0.55) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |