Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 3/20 | 0.41 |
| ▸ | TTK | P33981 | 3/20 | 0.39 |
| ▸ | FYN | P06241 | 6/20 | 0.38 |
| ▸ | CTSC | P53634 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127529 | 0.87 | RIPK2 (0.46) | RIPK2TTKFYNCTSCCTSL | |
| SCHEMBL7125034 | 0.84 | RIPK2 (0.42) | RIPK2TTKFYN | |
| SCHEMBL7124246 | 0.82 | RIPK2 (0.43) | RIPK2TTK | |
| SCHEMBL7118787 | 0.80 | EGFR (0.44) | FYNCTSCCTSLSTK10SLK | |
| SCHEMBL7160086 | 0.79 | RIPK2 (0.41) | RIPK2TTKFYN | |
| SCHEMBL7979380 | 0.77 | CDK8 (0.39) | CTSCCTSLSTK10SLK | |
| SCHEMBL7117952 | 0.77 | PIP4K2A (0.33) | FYNCTSC | |
| SCHEMBL7115900 | 0.75 | ABL1 (0.38) | — | |
| SCHEMBL7128092 | 0.74 | WNT1 (0.39) | CTSC | |
| SCHEMBL7129801 | 0.74 | RIPK2 (0.48) | RIPK2TTKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | RIPK2 3457/4885TTK 1660/4885FYN 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.