Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122378 | 0.87 | HSD17B10 (0.44) | HSD17B10HPGDALOX15NSD2KDM4E | |
| SCHEMBL7116818 | 0.87 | HSD17B10 (0.44) | HSD17B10HPGDALOX15NSD2KDM4E | |
| SCHEMBL7117874 | 0.83 | EGFR (0.43) | HSD17B10HPGDALOX15NSD2KDM4E | |
| SCHEMBL7157097 | 0.78 | HSD17B10 (0.47) | HSD17B10HPGDALOX15KDM4EPTGS2 | |
| SCHEMBL983374 | 0.74 | PDE4B (0.46) | HSD17B10HPGDKDM4ETHRATHRB | |
| SCHEMBL7119986 | 0.74 | HSD17B10 (0.46) | HSD17B10HPGDALOX15NSD2KDM4E | |
| SCHEMBL7121111 | 0.73 | EGFR (0.52) | HSD17B10HPGDKDM4ELMNACYP3A4 | |
| SCHEMBL7116141 | 0.72 | EGFR (0.49) | HSD17B10HPGDKDM4EPTGS2MAPT | |
| SCHEMBL50363 | 0.72 | MAPT (0.56) | HSD17B10HPGDALOX15KDM4EPTGS2 | |
| SCHEMBL4385363 | 0.72 | HSD17B10 (0.69) | HSD17B10HPGDALOX15NSD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1016648-B1 | PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES | ASAHI CHEMICAL IND (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6262210-B1 | TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-1016648-A1 | PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-07-05 | — | — | EP | disclosed |