SCHEMBL50363

SCHEMBL50363

O=C(Oc1ccccc1)c1cccc(-c2ccccc2)c1C(=O)Oc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
KDM4E B2RXH2 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
HSD17B10 Q99714 2/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
ALDH1A1 P00352 3/20 0.48
PDCD1 Q15116 3/20 0.47
CD274 Q9NZQ7 3/20 0.47
TSHR P16473 1/20 0.47
KMT2A Q03164 1/20 0.47
HNF4A P41235 1/20 0.46
BCAT2 O15382 1/20 0.44
LMNA P02545 2/20 0.43
PTK2B Q14289 1/20 0.43
NR4A2 P43354 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CHRM1 P11229 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27410294 0.92 MAPT (0.47) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL11015871 0.92 HNF4A (0.53) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL29159124 0.92 MAPT (0.54) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL3453990 0.86 HSD17B10 (0.61) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL28376689 0.83 MAPT (0.56) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL9306956 0.83 HNF4A (0.64) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL17309707 0.82 PDCD1 (0.65) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL2778716 0.82 MAPT (0.54) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL28161619 0.82 TSHR (0.58) MAPTKDM4ETDP1HSD17B10HPGD
SCHEMBL29112694 0.81 HSD17B10 (0.47) MAPTKDM4ETDP1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041574-A Catalyst component for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-05-02 CN claimed
US-4704118-A Ruminant dispensing device with thermo-activated memory ALZA CORPORATION (US) 1987-11-03 US claimed
US-4675174-A Veterinary dispenser delivering beneficial agent by gas power generated in situ ALZA CORPORATION (US) 1987-06-23 US claimed
US-4595583-A Delivery system controlled administration of beneficial agent to ruminants ALZA CORPORATION (US) 1986-06-17 US claimed
US-20240190040-A1 SLURRY FEEDSTOCK FOR EXTRUSION-BASED 3D PRINTING OF FUNCTIONALLY GRADED ARTICLES AND CASTING METAL/CERAMIC ARTICLE UNDER LOW PRESSURE AT ROOM TEMPERATURE, METHODS, AND SYSTEM THEREFOR SOLID LAB SDN BHD (MY) 2024-06-13 US disclosed
EP-4329969-A1 SLURRY FEEDSTOCK FOR EXTRUSION-BASED 3D PRINTING OF FUNCTIONALLY GRADED ARTICLES AND CASTING METAL/CERAMIC ARTICLE UNDER LOW PRESSURE AT ROOM TEMPERATURE, METHODS, AND SYSTEM THEREFOR Solid Lab SDN BHD (MY) 2024-03-06 EP disclosed
CN-117500624-A Slurry feedstock for extrusion-based 3D printed functionally graded articles and cast metal/ceramic articles at room temperature and low pressure, and methods and systems thereof 实力科技有限公司 2024-02-02 CN disclosed
US-11707451-B2 Pharmaceutical composition for modified release ASTELLAS PHARMA INC. (JP) 2023-07-25 US disclosed
CN-113677761-B Resin material and multilayer printed wiring board 积水化学工业株式会社 2023-03-24 CN disclosed
US-20220280418-A1 ORAL PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-09-08 US disclosed
EP-4015001-A1 ORAL PHARMACEUTICAL COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2022-06-22 EP disclosed
EP-4015002-A1 ORAL PHARMACEUTICAL COMPOSITION CONTAINING HETEROCYCLIC COMPOUND Otsuka Pharmaceutical Co., Ltd. (JP) 2022-06-22 EP disclosed
EP-0293066-A2 Dispenser comprising displaceable matrix with solid state properties ALZA CORPORATION (US) 1988-11-30 EP disclosed
US-4717566-A Dosage system and method of using same ALZA CORPORATION (US) 1988-01-05 US disclosed
US-4704118-A Ruminant dispensing device with thermo-activated memory ALZA CORPORATION (US) 1987-11-03 US disclosed
US-4675174-A Veterinary dispenser delivering beneficial agent by gas power generated in situ ALZA CORPORATION (US) 1987-06-23 US disclosed
US-4612186-A Method for establishing blood levels of biocide in animals ALZA CORPORATION (US) 1986-09-16 US disclosed
US-4595583-A Delivery system controlled administration of beneficial agent to ruminants ALZA CORPORATION (US) 1986-06-17 US disclosed
US-4310599-A LIGHT PIGMENT POWDER AND ELECTOCONDUCTIVE CARBON IN A BINDER AS ANTISTATIC LAYER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US disclosed
US-4241155-A METAL CHELATES CONTAINING PHOSPHORUS AND SULFUR FUJI PHOTO FILM CO., LTD. (JP) 1980-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707451-B2 Pharmaceutical composition for modified release SLC6A19, AASDHPPT, SLC6A15 MAPT 1010/4885KDM4E 993/4885TDP1 3311/4885
US-20220280418-A1 ORAL PHARMACEUTICAL COMPOSITION LIPA, CYP2C19, ABCB11 MAPT 1202/4885KDM4E 4698/4885TDP1 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.