Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CTSE | P14091 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26921324 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMMP13HTT | |
| SCHEMBL7119173 | 0.87 | MEN1 (0.54) | ALDH1A1MAPTSMN1; SMN2HTTNPC1 | |
| SCHEMBL21509690 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL27980531 | 0.85 | MAPT (0.53) | ALDH1A1MAPTLMNAHTTNPC1 | |
| SCHEMBL26923461 | 0.81 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2HTTNPC1 | |
| SCHEMBL30702542 | 0.81 | DPP4 (0.49) | ALDH1A1MAPTLMNAMMP2MMP13 | |
| SCHEMBL10039879 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL5901095 | 0.80 | KDM4E (0.62) | ALDH1A1MAPTMAPK1L3MBTL1ABCB1 | |
| SCHEMBL26922383 | 0.79 | NPC1 (0.45) | ALDH1A1MAPTHTTNPC1MAPK1 | |
| SCHEMBL31023690 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |