Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624234 | 0.74 | KDM4E (0.34) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7121039 | 0.73 | ALDH1A1 (0.36) | TXNRD1TXNRD3TXNRD2SMN1; SMN2KDM4E | |
| Bromide SCHEMBL1307432 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25434306 | 0.71 | CA1 (0.61) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL27753904 | 0.71 | CA1 (0.61) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL151213 | 0.71 | CA1 (0.61) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9730312 | 0.69 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL3307015 | 0.69 | CNR2 (0.51) | LMNAMEN1KMT2ASIGMAR1HTT | |
| Ammonia Solution, Strong SCHEMBL4268652 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31658961 | 0.69 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875247-B1 | Method for controlling the plasma level of lipoproteins | TNO (NL) | 2003-05-28 | — | — | EP | disclosed |
| US-6444664-B1 | ANTAGONIST OF PLATELET ACTIVATING FACTOR; BENZO- OR THIENOTRIAZOLO-DIAZEPINE OR BENZODIAZEPINE DERIVATIVE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST - NATUURWETEN SCHAPPELIJK ONDERZOEK (TNO) (NL) | 2002-09-03 | — | — | US | disclosed |
| EP-0875247-A1 | Method for controlling the plasma level of lipoproteins | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 1998-11-04 | — | — | EP | disclosed |