Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234287 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL6757787 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL22510633 | 0.70 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL21484686 | 0.70 | MAPT (0.87) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL8067428 | 0.70 | MAPT (0.87) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL18862294 | 0.69 | ALDH1A1 (0.68) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL1747883 | 0.67 | ALDH1A1 (0.63) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL13741468 | 0.67 | ALDH1A1 (0.64) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL6280916 | 0.67 | MAPK14 (0.67) | ALDH1A1MAPTMAPK1LMNAMEN1 | |
| SCHEMBL22114467 | 0.67 | FGFR1 (0.59) | ALDH1A1MAPTMAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | ALDH1A1 2482/4885MAPT 3896/4885MAPK1 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.