Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970067 | 0.96 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL16613793 | 0.90 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL22373757 | 0.87 | TSHR (0.63) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL17426746 | 0.87 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL8673499 | 0.86 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL799425 | 0.84 | NAMPT (0.58) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL4482387 | 0.84 | GFER (0.50) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL19349021 | 0.84 | NAMPT (0.58) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL10872706 | 0.82 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2GAANAAA | |
| SCHEMBL27366046 | 0.82 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2GAANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | claimed |
| US-20230140883-A1 | NOVEL MEMBRANES AND PREPARATION THEREOF | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2023-05-11 | — | — | US | disclosed |