Pimagedine

Pimagedine

SCHEMBL7121785

N=C(N)NN.O=C1NC(=O)C([N+](=O)[O-])C(=O)N1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RGS12 O14924 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL7124118 0.89 RGS12 (0.36) RGS12TSHR
SCHEMBL7117332 0.84
Hydrazine SCHEMBL7117203 0.81 MEN1 (0.36) RGS12TSHR
SCHEMBL131785 0.81 MEN1 (0.38) RGS12TSHR
Potassium SCHEMBL9326178 0.79 MEN1 (0.37) TSHR
Ammonia Solution, Strong SCHEMBL7125864 0.79 MEN1 (0.37) TSHR
Water SCHEMBL6481817 0.79 MEN1 (0.37) TSHR
Ammonia Solution, Strong SCHEMBL7125861 0.79 MEN1 (0.37) TSHR
SCHEMBL7117331 0.72 RGS12 (0.30) RGS12TSHR
Pimagedine SCHEMBL239259 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US claimed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US claimed
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US disclosed
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US disclosed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US disclosed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US disclosed