Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045637 | 1.00 | PTGER3 (0.56) | PTGER3PTGER1PTGER2PTGER4BACE1 | |
| SCHEMBL7501381 | 0.82 | PTGER3 (0.48) | PTGER3PTGER1PTGER2PTGER4PTGDR | |
| SCHEMBL7046284 | 0.81 | SMN1; SMN2 (0.56) | BACE1SMN1; SMN2ITGA4KDM4EALDH1A1 | |
| SCHEMBL7046280 | 0.81 | SMN1; SMN2 (0.56) | BACE1SMN1; SMN2ITGA4KDM4EALDH1A1 | |
| SCHEMBL7505191 | 0.78 | PTGER2 (0.52) | PTGER3PTGER1PTGER2PTGER4PTGDR | |
| SCHEMBL7115616 | 0.78 | PTGER2 (0.52) | PTGER3PTGER1PTGER2PTGER4PTGDR | |
| SCHEMBL8999206 | 0.78 | HDAC8 (0.59) | PTGER3PTGER1PTGER2PTGER4BACE1 | |
| SCHEMBL7050014 | 0.77 | PTGER3 (0.42) | PTGER3PTGER1PTGER2PTGER4PTGDR | |
| SCHEMBL7050017 | 0.77 | PTGER3 (0.42) | PTGER3PTGER1PTGER2PTGER4PTGDR | |
| SCHEMBL1981788 | 0.74 | BACE1 (0.64) | PTGER3PTGER1PTGER2PTGER4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220392-A1 | Fatty acid synthase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-27 | — | — | US | disclosed |
| US-6498187-B1 | SUCH AS 2'-(6-CHLOROPIPERONYL)-3-(2,6-DICHLOROBENZYLOXY)-CINNAMIC ACID; ANTIBIOTICS | SMITHKLINE BEECHAM CORPORATION | 2002-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220392-A1 | Fatty acid synthase inhibitors | FASN, FADS1, FADS2 | PTGER3 2414/4885PTGER1 2201/4885PTGER2 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.