⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654367 | 0.66 | MAPK1 (0.30) | — | |
| SCHEMBL7125173 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL2210250 | 0.64 | MAPK1 (0.32) | — | |
| SCHEMBL3610364 | 0.60 | MEN1 (0.32) | — | |
| SCHEMBL3465268 | 0.59 | — | — | |
| SCHEMBL11240031 | 0.59 | — | — | |
| SCHEMBL10934052 | 0.55 | — | — | |
| SCHEMBL12687558 | 0.55 | — | — | |
| SCHEMBL10934045 | 0.55 | — | — | |
| SCHEMBL2611974 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796849-B1 | NOVEL POLYCYCLIC AMINOPYRIDINE COMPOUNDS AS ACETYLCHOLINESTERASE INHIBITORS, PREPARATION PROCESS AND USE THEREOF | MEDICHEM SA (ES) | 2003-11-19 | — | — | EP | disclosed |
| US-5965569-A | TREATING MEMORY DISORDERS SUCH AS SENILE DEMENTIA OR ALZHEIMER'S DISEASE | MEDICHEM, S.A. (ES) | 1999-10-12 | — | — | US | disclosed |
| EP-0796849-A1 | NOVEL POLYCYCLIC AMINOPYRIDINE COMPOUNDS AS ACETYLCHOLINESTERASE INHIBITORS, PREPARATION PROCESS AND USE THEREOF | Camps Garcia, Pelayo (ES) | 1997-09-24 | — | — | EP | disclosed |