SCHEMBL712279

SCHEMBL712279

NC(=O)N(N)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.54
ALDH1A1 P00352 5/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
ATM Q13315 1/20 0.48
POLB P06746 2/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 2/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 2/20 0.44
TSHR P16473 2/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30821401 0.98 NPSR1 (0.52) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL27945332 0.91 ALDH1A1 (0.50) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL27552505 0.87 NPSR1 (0.36) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL28135524 0.83 MEN1 (0.41) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL75885 0.82 NPSR1 (0.64) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL10348556 0.82 NPSR1 (0.64) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL75883 0.82 NPSR1 (0.64) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL4103979 0.82 NPSR1 (0.56) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL28148401 0.82 NPSR1 (0.64) NPSR1ALDH1A1L3MBTL1TDP1ATM
SCHEMBL10783514 0.81 NPSR1 (0.50) NPSR1ALDH1A1L3MBTL1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264667-A High expansion rate silicone rubber cold shrink tube 任丘市恒威通信设备有限公司 2025-01-07 CN claimed
CN-101922376-B Corrosion resistant insert for a cylinder head GM GLOBAL TECH OPERATIONS INC 2013-04-24 CN claimed
CN-102796091-A Substituted oxazolidinone compound and preparation method and application thereof UNIV PEKING FOUNDER GROUP CO 2012-11-28 CN claimed
US-7704995-B2 Protein kinase modulators and methods of use EXELIXIS, INC. (US) 2010-04-27 US claimed
EP-2118064-A2 6-AMINOISOQUINOLINE COMPOUNDS USEFUL AS KINASE MODULATORS AERIE PHARMACEUTICALS, INC. (US) 2009-11-18 EP claimed
WO-2008086269-A2 6-AMINOISOQUINOLINE COMPOUNDS USEFUL AS KINASE MODULATORS AERIE PHARMACEUTICALS, INC. (US) 2008-07-17 WO claimed
US-20060211709-A1 Protein kinase modulators and methods of use EXELIXIS, INC. 2006-09-21 US claimed
EP-1501814-A1 SEMICARBAZIDE DERIVATIVES FOR COMBATING THROMBOEMBOLIC DISEASES MERCK PATENT GmbH (DE) 2005-02-02 EP claimed
WO-2003093254-A1 SEMICARBAZIDE DERIVATIVES FOR COMBATING THROMBOEMBOLIC DISEASES MERCK PATENT GMBH (DE) 2003-11-13 WO claimed
EP-0192242-B1 SUBSTITUTED AMINOPHENYLUREA DERIVATIVES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-11-07 EP claimed
US-4803223-A ANTITUMOR AGENTS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-02-07 US claimed
EP-0187121-B1 HEAT-CURABLE EPOXY RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1988-07-13 EP claimed
US-4645818-A CONTAINING AN AMIDOARYLUREA CIBA-GEIGY CORPORATION (US) 1987-02-24 US claimed
EP-0192242-A1 Substituted aminophenylurea derivatives TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-27 EP claimed
US-4358611-A FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE SHELL OIL COMPANY (US) 1982-11-09 US claimed
US-3983564-A Image recording member CANON KABUSHIKI KAISHA (JA) 1976-09-28 US claimed
US-12559455-B2 Compound as a UBR box domain ligand AUTOTAC INC. (KR) 2026-02-24 US disclosed
CN-120005335-A Perfluororubber composition, preparation method thereof and product 上海芯密科技股份有限公司 2025-05-16 CN disclosed
US-3965087-A Trisazo dye containing a diphenylenesulfone structure SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-06-22 US disclosed
US-3951941-A POLYAZODYE SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211709-A1 Protein kinase modulators and methods of use GRK2, MAP4K2, MAPKAPK2 NPSR1 768/4885ALDH1A1 3298/4885L3MBTL1 2736/4885
US-12559455-B2 Compound as a UBR box domain ligand UBR4, UBTF, UBQLN1 NPSR1 969/4885ALDH1A1 1486/4885L3MBTL1 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.