Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7116453 | 0.97 | ACP3 (0.40) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL7116499 | 0.89 | ESR1 (0.42) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL4194507 | 0.83 | HTT (0.47) | HTTSLC6A2SLC6A4HTR2AHRH1 | |
| Diethylamine SCHEMBL8165175 | 0.82 | ACP3 (0.42) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL4185484 | 0.82 | ACP3 (0.42) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL6512053 | 0.82 | ACP3 (0.42) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL8172450 | 0.78 | ESR1 (0.42) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL8179089 | 0.78 | ACP3 (0.39) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL6271332 | 0.77 | ESR1 (0.45) | ACP3HTTOPRM1SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL6365629 | 0.77 | ESR1 (0.45) | ACP3HTTOPRM1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828182-B1 | Storage-stable photoimageable compositions with improved leuco dye | DU PONT (US) | 2003-11-19 | — | — | EP | claimed |
| US-5744280-A | MONOCHROME IMAGES;IMPROVED CONTRAST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-28 | — | — | US | claimed |