Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL8165175 | 0.96 | ACP3 (0.42) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL6512053 | 0.96 | ACP3 (0.42) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL11318959 | 0.91 | ESR1 (0.41) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL6365629 | 0.88 | ESR1 (0.45) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL237985 | 0.86 | ESR1 (0.43) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL2422170 | 0.86 | ACP3 (0.52) | ACP3SLC6A2SLC6A4CYP2D6CYP2C9 | |
| Diethylamine SCHEMBL556784 | 0.86 | ALDH1A1 (0.45) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL10780343 | 0.85 | ESR1 (0.42) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL7116453 | 0.82 | ACP3 (0.40) | ACP3HTTSLC6A2SLC6A4CYP2D6 | |
| Diethylamine SCHEMBL7122867 | 0.82 | ACP3 (0.40) | ACP3HTTSLC6A2SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264212-B1 | ELEMENTS FOR FORMING PRINT-OUT IMAGES | DU PONT (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-0889363-B1 | Near IR sensitive photoimageable/photopolymerizable compositions, media, and associated processes | DU PONT (US) | 2005-10-05 | — | — | EP | disclosed |
| US-6869755-B2 | Elements for forming print-out images | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-03-22 | — | — | US | disclosed |
| EP-0828182-B1 | Storage-stable photoimageable compositions with improved leuco dye | DU PONT (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-1264212-A2 | ELEMENTS FOR FORMING PRINT-OUT IMAGES | E. I. du Pont de Nemours and Company (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020146649-A1 | Elements for forming print-out images | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-10-10 | — | — | US | disclosed |
| WO-2001067175-A2 | ELEMENTS FOR FORMING PRINT-OUT IMAGES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-13 | — | — | WO | disclosed |
| EP-0889363-A1 | Near IR sensitive photoimageable/photopolymerizable compositions, media, and associated processes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0828182-A1 | Storage-stable photoimageable compositions with improved leuco dye | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-11 | — | — | EP | disclosed |