Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 15/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118585 | 0.97 | MEN1 (0.44) | MEN1KMT2ATDP1MAP2K1CA2 | |
| SCHEMBL7461661 | 0.90 | MEN1 (0.45) | MEN1KMT2ATDP1MAP2K1CA2 | |
| SCHEMBL7454190 | 0.89 | MEN1 (0.44) | MEN1KMT2ATDP1MAP2K1CA2 | |
| SCHEMBL7785868 | 0.87 | CXCR3 (0.34) | MEN1KMT2ATDP1CXCR3HDAC3 | |
| SCHEMBL7125539 | 0.86 | MEN1 (0.45) | MEN1KMT2ATDP1MAP2K1CA2 | |
| SCHEMBL7123642 | 0.85 | MEN1 (0.47) | MEN1KMT2ATDP1MAP2K1CA2 | |
| SCHEMBL6262764 | 0.82 | MEN1 (0.58) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL7123660 | 0.82 | MEN1 (0.45) | MEN1KMT2ATDP1MAP2K1CA2 | |
| SCHEMBL6263014 | 0.80 | MEN1 (0.59) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL7464207 | 0.79 | CCR6 (0.34) | MEN1KMT2ATDP1MAP2K1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504401-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1202724-A2 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001005393-A2 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-01-25 | — | — | WO | claimed |