Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.76 |
| ▸ | PDE4A | P27815 | 19/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546049 | 0.90 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546052 | 0.90 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6546406 | 0.90 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6635890 | 0.89 | PDE4B (0.81) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL433298 | 0.88 | PDE4B (0.68) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7119026 | 0.88 | PDE4B (0.68) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29351482 | 0.88 | PDE4B (0.68) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545916 | 0.88 | PDE4B (0.86) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6545912 | 0.88 | PDE4B (0.86) | PDE4BPDE4APDE4CPDE4D | |
| Cilomilast SCHEMBL26372 | 0.87 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200388-A4 | METHOD FOR PREPARING CYCLOHEXANE CARBOXYLIC ACIDS | SMITHKLINE BEECHAM CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1200388-A1 | METHOD FOR PREPARING CYCLOHEXANE CARBOXYLIC ACIDS | SmithKline Beecham Corporation (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001010817-A1 | METHOD FOR PREPARING CYCLOHEXANE CARBOXYLIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-02-15 | — | — | WO | disclosed |