Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125923 | 0.91 | DYRK1A (0.57) | DYRK1ARAB9AMAPTTHRBPOLB | |
| SCHEMBL7129461 | 0.91 | DYRK1A (0.70) | DYRK1ARAB9AMAPTPOLBLMNA | |
| SCHEMBL7125975 | 0.89 | MAPT (0.62) | DYRK1ARAB9AMAPTTHRBPOLB | |
| SCHEMBL7124202 | 0.88 | DYRK1A (0.54) | DYRK1ARAB9AMAPTTHRBPOLB | |
| SCHEMBL7162058 | 0.88 | DYRK1A (0.64) | DYRK1ARAB9AMAPTPOLBLMNA | |
| SCHEMBL7127487 | 0.88 | MMP13 (0.74) | DYRK1ARAB9AMAPTPOLBLMNA | |
| SCHEMBL7124297 | 0.87 | DYRK1A (0.61) | DYRK1ARAB9AMAPTPOLBLMNA | |
| SCHEMBL7119606 | 0.86 | MAPT (0.61) | DYRK1ARAB9AMAPTPOLBLMNA | |
| SCHEMBL7127519 | 0.85 | SCD (0.73) | DYRK1ARAB9AMAPTPOLBLMNA | |
| SCHEMBL5731624 | 0.84 | MAPT (0.69) | DYRK1ARAB9AMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | claimed |
| CN-1440383-A | PPAR gamma modulators | SANKYO CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | DYRK1A 3783/4885RAB9A 1179/4885MAPT 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.