Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745316 | 0.80 | MGAM (0.54) | MGAMHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL744938 | 0.79 | MEN1 (0.46) | KMT2AMEN1ALDH1A1MAPTHCRTR1 | |
| SCHEMBL5156183 | 0.78 | MGAM (0.57) | MGAMHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL5155140 | 0.74 | ALDH1A1 (0.49) | MGAMHPGDALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11052630 | 0.74 | MAPT (0.70) | MGAMHPGDALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL747904 | 0.74 | HCRTR1 (0.66) | MGAMKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL746415 | 0.73 | MGAM (0.47) | MGAMHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL5152366 | 0.73 | MGAM (0.64) | MGAMHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL5151401 | 0.73 | KMT2A (0.50) | MGAMHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL5152422 | 0.73 | MGAM (0.58) | MGAMHPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017965-A1 | 1,3-THIAZOLIN-4-ONES AS THERAPEUTIC COMPOUNDS IN THE TREATMENT OF PAIN | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |