Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 9/20 | 0.60 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757775 | 0.90 | LTB4R (0.60) | LTB4RCTSAMAPTNPC1LMNA | |
| SCHEMBL7123679 | 0.90 | LTB4R (0.76) | LTB4R | |
| SCHEMBL6757555 | 0.86 | LTB4R (0.78) | LTB4R | |
| SCHEMBL6759579 | 0.86 | LTB4R (0.56) | LTB4RCTSAMAPTALDH1A1 | |
| SCHEMBL6757772 | 0.80 | LTB4R (0.76) | LTB4R | |
| SCHEMBL6757485 | 0.80 | LTB4R (0.51) | LTB4RCTSA | |
| SCHEMBL6757525 | 0.78 | LTB4R (0.53) | LTB4RALDH1A1L3MBTL1 | |
| SCHEMBL6757471 | 0.77 | LTB4R (0.51) | LTB4RCTSAMAPTNPC1LMNA | |
| SCHEMBL6759621 | 0.77 | LTB4R (0.53) | LTB4RCTSAMAPTADORA1KDM4E | |
| SCHEMBL6759576 | 0.76 | LTB4R (0.69) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099810-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |