Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971745 | 0.84 | ALDH1A1 (0.46) | TSHRALDH1A1MAPK1ALOX15HTT | |
| SCHEMBL11520669 | 0.82 | TSHR (0.37) | TSHRALDH1A1KCNN4 | |
| SCHEMBL2449393 | 0.81 | TSHR (0.39) | TSHRALDH1A1MAPK1KCNN4ALOX15 | |
| SCHEMBL11019163 | 0.81 | MAPK1 (0.39) | TSHRALDH1A1MAPK1KCNN4ALOX15 | |
| SCHEMBL29113996 | 0.81 | TSHR (0.39) | TSHRALDH1A1MAPK1KCNN4KIF11 | |
| SCHEMBL89302 | 0.79 | TSHR (0.37) | TSHRALDH1A1MAPK1KCNN4ALOX15 | |
| SCHEMBL25430781 | 0.78 | ALDH1A1 (0.44) | TSHRALDH1A1MAPK1KCNN4ALOX15 | |
| SCHEMBL89303 | 0.76 | ALDH1A1 (0.35) | TSHRALDH1A1MAPK1KCNN4ALOX15 | |
| SCHEMBL4560379 | 0.76 | ALDH1A1 (0.35) | TSHRALDH1A1MAPK1KCNN4ALOX15 | |
| SCHEMBL15232972 | 0.76 | MAPK1 (0.35) | TSHRALDH1A1MAPK1KCNN4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065089-A1 | Aqueous dispersion in a formulation for floor adhesives | ATOFINA (FR) | 2003-04-03 | — | — | US | disclosed |
| US-4761358-A | Electrostatographic encapsulated toner | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| US-4191705-A | Process for the preparation of carbonic acid esters of polyester-polyols | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |