Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631891 | 0.84 | MEN1 (0.46) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL7103060 | 0.83 | POLB (0.46) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL7099367 | 0.81 | MEN1 (0.46) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL7098427 | 0.80 | MEN1 (0.46) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL7153122 | 0.79 | MEN1 (0.45) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL13261760 | 0.79 | MEN1 (0.44) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL7101207 | 0.76 | KMT2A (0.58) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6630986 | 0.73 | MEN1 (0.47) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL6630982 | 0.70 | MEN1 (0.44) | MEN1KMT2APOLBAPAF1ALDH1A1 | |
| SCHEMBL7097929 | 0.70 | MEN1 (0.44) | MEN1KMT2APOLBAPAF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670383-B2 | Such as 5-(2-hydroxy-ethoxy)-2,2-dimethyl-6-propionyl-10-propyl-2H-pyrano(2,3 -f)chromen-8-one for treatment of Mycobacterium infection, AIDS, and tuburculosis | ADVANCED LIFE SCIENCES, INC. | 2003-12-30 | — | — | US | disclosed |