Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124036 | 0.73 | PARP1 (0.40) | PARP1ADRB2CYP2D6ADRB1HIF1A | |
| SCHEMBL7124040 | 0.72 | PARP1 (0.39) | PARP1ADRB2TRPV3KDM4ECYP1A2 | |
| SCHEMBL7122691 | 0.71 | PARP1 (0.40) | PARP1TRPV3KDM4ELMNACYP1A2 | |
| SCHEMBL7118786 | 0.69 | PARP1 (0.43) | PARP1TRPV3KDM4ELMNAMEN1 | |
| SCHEMBL7583585 | 0.64 | PARP1 (0.43) | PARP1TRPV3KDM4ELMNAMEN1 | |
| SCHEMBL1753930 | 0.64 | MEN1 (0.59) | PARP1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29441293 | 0.64 | MEN1 (0.59) | PARP1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8888541 | 0.64 | PARP1 (0.54) | PARP1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL564494 | 0.64 | PARP1 (0.58) | PARP1KDM4ELMNACYP1A2TSHR | |
| SCHEMBL29729655 | 0.64 | PARP1 (0.58) | PARP1KDM4ELMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030097000-A1 | 2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof | SANOFI-SYNTHELABO (FR) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097000-A1 | 2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof | CYP2F1, CYP4F2, CYP4F3 | PARP1 1508/4885ADRB2 297/4885PTGS2 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.