Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 4/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124040 | 0.78 | PARP1 (0.39) | PARP1ADRB1ADRB2CYP2D6HIF1A | |
| SCHEMBL7124045 | 0.73 | PARP1 (0.40) | PARP1ADRB1ADRB2CYP2D6NFKB1 | |
| SCHEMBL7122691 | 0.73 | PARP1 (0.40) | PARP1CYP2D6NFKB1CTSA | |
| SCHEMBL10875410 | 0.71 | ADRB1 (0.50) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL24630910 | 0.71 | HIF1A (0.51) | PARP1ADRB1ADRB2CYP2D6NFKB1 | |
| SCHEMBL22864225 | 0.71 | HIF1A (0.51) | PARP1ADRB1ADRB2CYP2D6NFKB1 | |
| SCHEMBL22864228 | 0.68 | ADRB1 (0.62) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL24630909 | 0.68 | ADRB1 (0.62) | ADRB1ADRB2CYP2D6NFKB1HIF1A | |
| SCHEMBL7118786 | 0.68 | PARP1 (0.43) | PARP1NFKB1CTSA | |
| SCHEMBL22864043 | 0.68 | ADRB2 (0.47) | ADRB1ADRB2CYP2D6NFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030097000-A1 | 2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof | SANOFI-SYNTHELABO (FR) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097000-A1 | 2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof | CYP2F1, CYP4F2, CYP4F3 | PARP1 1508/4885ADRB1 340/4885ADRB2 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.