Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6367576 | 0.99 | CASR (0.43) | CASRF10PRSS1POLBTPSAB1 | |
| Hydrochloric Acid SCHEMBL6365782 | 0.90 | CASR (0.44) | CASRF10PRSS1TPSAB1ITGB3 | |
| Hydrochloric Acid SCHEMBL6365326 | 0.89 | CASR (0.42) | CASRF10PRSS1POLBTPSAB1 | |
| Hydrochloric Acid SCHEMBL6365798 | 0.85 | F2 (0.46) | F10PRSS1POLBF2 | |
| Hydrochloric Acid SCHEMBL6372912 | 0.84 | ITGB3 (0.49) | CASRF10PRSS1POLBTPSAB1 | |
| Hydrochloric Acid SCHEMBL6372927 | 0.82 | ITGB3 (0.48) | CASRF10PRSS1TPSAB1ITGB3 | |
| Hydrochloric Acid SCHEMBL6367337 | 0.82 | SMN1; SMN2 (0.51) | F10PRSS1POLB | |
| Hydrochloric Acid SCHEMBL6365717 | 0.80 | CASR (0.42) | CASRF10PRSS1TPSAB1ITGB3 | |
| Hydrochloric Acid SCHEMBL6371655 | 0.79 | EPHX2 (0.44) | F10PRSS1POLBEPHX2 | |
| Hydrochloric Acid SCHEMBL6365494 | 0.79 | MEN1 (0.47) | ITGB3EPHX2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206444-B1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2003-11-12 | — | — | EP | disclosed |