Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.60 |
| ▸ | FABP3 | P05413 | 5/20 | 0.54 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7120710 | 0.97 | LPAR3 (0.60) | LPAR3LPAR2LPAR1FABP3P2RY10 | |
| Phosphoric Acid SCHEMBL8390953 | 0.95 | LPAR3 (0.56) | LPAR3LPAR2LPAR1FABP3P2RY10 | |
| Phosphoric Acid SCHEMBL8390957 | 0.95 | LPAR3 (0.56) | LPAR3LPAR2LPAR1FABP3P2RY10 | |
| Phosphoric Acid SCHEMBL29085498 | 0.92 | LPAR3 (0.58) | LPAR3LPAR2LPAR1FABP3P2RY10 | |
| Phosphoric Acid SCHEMBL570799 | 0.91 | LPAR3 (0.56) | LPAR3LPAR2LPAR1P2RY10 | |
| Phosphoric Acid SCHEMBL1811632 | 0.91 | LPAR3 (0.56) | LPAR3LPAR2LPAR1P2RY10 | |
| Phosphoric Acid SCHEMBL570800 | 0.91 | LPAR3 (0.56) | LPAR3LPAR2LPAR1P2RY10 | |
| Phosphoric Acid SCHEMBL943055 | 0.91 | LPAR3 (0.66) | LPAR3LPAR2LPAR1P2RY10 | |
| Phosphoric Acid SCHEMBL943057 | 0.91 | LPAR3 (0.66) | LPAR3LPAR2LPAR1P2RY10 | |
| Phosphoric Acid SCHEMBL8372349 | 0.89 | LPAR3 (0.64) | LPAR3LPAR2LPAR1FABP3P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785247-B1 | REFRIGERATOR OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2003-11-19 | — | — | EP | claimed |
| US-5858266-A | CONTAINING A HYDROFLUOROCARBON, A PHOSPHOROUS COMPOUND AND AN OXYGEN-CONTAINING ORGANIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 1999-01-12 | — | — | US | claimed |
| EP-0785247-A1 | REFRIGERATOR OIL COMPOSITION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-07-23 | — | — | EP | claimed |
| US-5858266-A | CONTAINING A HYDROFLUOROCARBON, A PHOSPHOROUS COMPOUND AND AN OXYGEN-CONTAINING ORGANIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |