SCHEMBL7124418

SCHEMBL7124418

CC(=O)N(CC(=O)O)C(C)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
EYA2 O00167 1/20 0.43
APP P05067 1/20 0.43
ACE P12821 1/20 0.43
CHRM2 P08172 4/20 0.41
LMNA P02545 3/20 0.41
BLM P54132 2/20 0.41
PMP22 Q01453 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ADRA2A P08913 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
CYP2C19 P33261 1/20 0.41
ADRA1A P35348 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL29281297 0.89 GLRA1 (0.36) TDP1EYA2APPACECHRM2
SCHEMBL29112235 0.82 FFAR3 (0.41) TDP1EYA2APPACECHRM2
SCHEMBL28474533 0.80 PHF8 (0.46) TDP1EYA2APPACECHRM2
SCHEMBL21955799 0.80 GLRA1 (0.39) TDP1EYA2APPACECHRM2
SCHEMBL11298271 0.78 ALDH1A1 (0.38) TDP1LMNA
SCHEMBL2140134 0.78 CHRM2 (0.40) TDP1CHRM2LMNACHRM4CHRM5
SCHEMBL321404 0.77 TDP1 (0.39) TDP1EYA2APPACECHRM2
SCHEMBL2687920 0.75 TDP1 (0.43) TDP1EYA2APPACECHRM2
Hydrogen Peroxide SCHEMBL7571602 0.73 CHRM2 (0.42) TDP1EYA2APPACECHRM2
SCHEMBL6243323 0.73 TDP1 (0.47) TDP1EYA2APPACECHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476696-B Anti-trypanosome and anti-leishmania agents for animals and humans 细胞基因公司 2022-06-10 CN claimed
CN-113632205-B Polishing liquid and polishing method 株式会社力森诺科 2024-12-20 CN disclosed
CN-117883634-A Hemostatic bone repair hydrogel and preparation method and application thereof 广东省科学院生物与医学工程研究所 2024-04-16 CN disclosed
CN-115932277-A Breast cancer diagnosis marker, screening method and quantification method thereof, and diagnostic model construction method and application 北京大学 2023-04-07 CN disclosed
CN-109476696-B Anti-trypanosome and anti-leishmania agents for animals and humans 细胞基因公司 2022-06-10 CN disclosed
CN-104945287-B A kind of synthetic method of the acid inner salt compound of amidine 苏州大学张家港工业技术研究院 2017-06-13 CN disclosed
CN-104961660-B A kind of acid inner salt compound of amidine 苏州大学张家港工业技术研究院 2017-06-13 CN disclosed
CN-105296207-A Experimental utensil cleaning liquid for cytobiological and preparation method of experimental utensil cleaning liquid UNIV QIQIHAR MEDICAL 2016-02-03 CN disclosed
CN-104961660-A Inner salt compound of amidine sulfonic acid ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2015-10-07 CN disclosed
CN-104945287-A Synthetic method of sulfonic acid inner salt compound of amidine ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2015-09-30 CN disclosed
CN-104744250-A Method for synthesizing diacetylglycine JIANGSU LEMON CHEMICAL & TECHNOLOGY CO LTD 2015-07-01 CN disclosed
CN-104744250-A Method for synthesizing diacetylglycine JIANGSU LEMON CHEMICAL & TECHNOLOGY CO LTD 2015-07-01 CN disclosed
US-6670159-B1 Monoamidating a proteinaceous molecule containing a primary amine group (e.g., horseradish peroxidase or alkaline phosphatase) with nitrilotriacetic acid in the presence of a carbodiimide PIERCE BIOTECHNOLOGY, INC. 2003-12-30 US disclosed
US-6670159-B1 Monoamidating a proteinaceous molecule containing a primary amine group (e.g., horseradish peroxidase or alkaline phosphatase) with nitrilotriacetic acid in the presence of a carbodiimide PIERCE BIOTECHNOLOGY, INC. 2003-12-30 US disclosed
US-6670159-B1 Monoamidating a proteinaceous molecule containing a primary amine group (e.g., horseradish peroxidase or alkaline phosphatase) with nitrilotriacetic acid in the presence of a carbodiimide PIERCE BIOTECHNOLOGY, INC. 2003-12-30 US disclosed