Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.61 |
| ▸ | CDK9 | P50750 | 5/20 | 0.61 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.51 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713138 | 0.88 | SCN3A (0.60) | CCNT1CDK9SCN3AIKBKBSYK | |
| SCHEMBL711709 | 0.87 | CCNT1 (0.61) | CCNT1CDK9SCN3AIKBKBPKM | |
| SCHEMBL711574 | 0.87 | CCNT1 (0.59) | CCNT1CDK9SCN3AIKBKBPKM | |
| SCHEMBL713573 | 0.83 | CCNT1 (0.70) | CCNT1CDK9IKBKBPKMEGFR | |
| SCHEMBL712626 | 0.80 | CCNA2 (0.70) | CCNT1CDK9IKBKBPKMSYK | |
| SCHEMBL713988 | 0.79 | ALDH1A1 (0.64) | CCNT1CDK9SCN3AIKBKBPKM | |
| SCHEMBL4146308 | 0.76 | CCNT1 (0.66) | CCNT1CDK9IKBKBPKMSYK | |
| SCHEMBL16646055 | 0.75 | SCN3A (0.68) | SCN3APKMSCN1ASCN5ASCN8A | |
| Hydrochloric Acid SCHEMBL8933679 | 0.74 | EGFR (0.60) | CCNT1CDK9SCN3AIKBKBPKM | |
| SCHEMBL3050459 | 0.74 | SCN3A (0.65) | SCN3APKMSCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | claimed |
| US-8124610-B2 | Sodium channel inhibitors | ICAGEN INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2173743-A2 | SODIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | ICAGEN (US) | 2009-01-22 | — | — | US | disclosed |
| WO-2009012242-A2 | SODIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023740-A1 | SODIUM CHANNEL INHIBITORS | TRPV1, SCN1A, SCN2A | CCNT1 3878/4885CDK9 2777/4885SCN3A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.