Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 2/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752464 | 0.88 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL6579476 | 0.76 | KCNN4 (0.40) | TACR1KCNN4KLK7KLK5 | |
| SCHEMBL5755094 | 0.74 | CETP (0.37) | KLK7KLK5 | |
| SCHEMBL5752417 | 0.73 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL5753504 | 0.73 | HCRTR1 (0.37) | KLK7KLK5 | |
| SCHEMBL5751036 | 0.72 | GRM5 (0.36) | — | |
| SCHEMBL5750445 | 0.71 | HCRTR1 (0.37) | KLK7KLK5 | |
| SCHEMBL7124729 | 0.69 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL5750694 | 0.65 | CTSS (0.37) | KLK5SCN9A | |
| SCHEMBL5752903 | 0.65 | KCNN4 (0.35) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |