Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607299 | 0.89 | ESR1 (0.50) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL5727621 | 0.87 | MAPT (0.59) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL6206994 | 0.84 | MAPK1 (0.53) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL5727619 | 0.81 | ESR1 (0.48) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL11764887 | 0.81 | IDO1 (0.51) | MTNR1AMTNR1B | |
| SCHEMBL27765661 | 0.80 | CA12 (0.43) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL27649490 | 0.74 | CYP11B1 (0.43) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL8588897 | 0.73 | ESR1 (0.45) | KMT2AMEN1CYP3A4ALOX15MAPK1 | |
| SCHEMBL28542001 | 0.73 | CYP3A4 (0.39) | MAPTKMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL27984983 | 0.73 | KMT2A (0.44) | MAPTKMT2AMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011446-A1 | INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |