Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727621 | 0.92 | MAPT (0.59) | ESR1MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL7125261 | 0.89 | MAPT (0.56) | ESR1MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL7123434 | 0.84 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27332720 | 0.82 | ALDH1A1 (0.51) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6206994 | 0.81 | MAPK1 (0.53) | ESR1MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL6292654 | 0.80 | PPARD (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5727619 | 0.79 | ESR1 (0.48) | ESR1MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL5726773 | 0.77 | MTNR1B (0.52) | ESR1MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL9404746 | 0.74 | MAPT (0.89) | ESR1MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL19393249 | 0.74 | MAPT (0.89) | ESR1MAPTLMNAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100591657-C | Indane acetic acid compound | BAYER PHARMACEUTICALS CORP | 2010-02-24 | — | — | CN | disclosed |
| CN-100528850-C | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | BAYER AG (US) | 2009-08-19 | — | — | CN | disclosed |
| CN-1854118-A | Indane acetic acid compound | BAYER PHARMACEUTICALS CORP (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1558905-A | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | ������˹ҩƷ��˾ | 2004-12-29 | — | — | CN | disclosed |