Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353612 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL29407435 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL4215764 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL1467411 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL38951 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL9858733 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL29446143 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL1468260 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL7887565 | 1.00 | PTPN11 (0.54) | PTPN11NR5A1PTPN1PDK2RARB | |
| SCHEMBL3690940 | 0.99 | PTPN11 (0.52) | PTPN11NR5A1PTPN1PDK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225192-A1 | Mxitures of 2-(2-hydroxy-4(3-butoxy-2-hydroxypropyloxy)-phenyl )-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and hindered amine light stabilizers, used for stabilization of curable polycarbonates | BIRBAUM JEAN-LUC (CH) | 2003-12-04 | — | — | US | disclosed |
| US-6608122-B1 | O-Hydroxyphenyl-s-triazines in combination with sterically hindered amines of the polyalkylpiperidine type | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-19 | — | — | US | disclosed |
| US-5736597-A | USING O-HYDROXYPHENYL-S-TRIAZINE AND STERIC HINDERED AMINE OF THE POLYALKYLPIPERIDINE TYPE | CIBA-GEIGY CORPORATION (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0434608-B1 | Stabilized organic material | CIBA GEIGY AG (CH) | 1997-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225192-A1 | Mxitures of 2-(2-hydroxy-4(3-butoxy-2-hydroxypropyloxy)-phenyl )-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and hindered amine light stabilizers, used for stabilization of curable polycarbonates | SIGMAR1, H1-2, H1-5 | PTPN11 2579/4885NR5A1 3359/4885PTPN1 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.