Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003121 | 0.73 | TSHR (0.53) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3982616 | 0.73 | TSHR (0.48) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6140950 | 0.72 | CES2 (0.58) | MGLLALDH1A1RAB9AHSD11B1KDM2B | |
| SCHEMBL11190518 | 0.72 | KMT2A (0.54) | MGLLALDH1A1RAB9AHSD11B1KDM2B | |
| SCHEMBL6749308 | 0.72 | KDM4E (0.61) | ALDH1A1HSD11B1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5146481 | 0.72 | TSHR (0.56) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL14811388 | 0.71 | MEN1 (0.58) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6749559 | 0.71 | KDM4E (0.63) | ALDH1A1HSD11B1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14811167 | 0.70 | KMT2A (0.46) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7077511 | 0.70 | HDAC3 (0.54) | LMNAALDH1A1FAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003525203-A | — | — | 2003-08-26 | — | — | JP | claimed |
| EP-1163213-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2001-12-19 | — | — | EP | claimed |
| WO-2000056704-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2000-09-28 | — | — | WO | claimed |