Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DVL1 | O14640 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490670 | 0.78 | HDAC1 (0.44) | HDAC1RXFP1KMT2APTPN1 | |
| SCHEMBL28626965 | 0.77 | AAK1 (0.46) | HDAC1AAK1MEN1KMT2A | |
| SCHEMBL7381558 | 0.75 | CTSV (0.52) | HDAC1DVL1MEN1KMT2ACTSV | |
| SCHEMBL5563988 | 0.74 | CYP1A2 (0.45) | HDAC1RXFP1AAK1MEN1KMT2A | |
| SCHEMBL246277 | 0.73 | AAK1 (0.46) | HDAC1AAK1MEN1KMT2A | |
| SCHEMBL29765467 | 0.73 | AAK1 (0.46) | HDAC1AAK1MEN1KMT2A | |
| SCHEMBL18687357 | 0.72 | SIRT2 (0.50) | HDAC1MEN1KMT2ASIRT2CTSV | |
| SCHEMBL15153398 | 0.71 | FFAR1 (0.56) | — | |
| SCHEMBL3410364 | 0.71 | HPGD (0.49) | AAK1 | |
| SCHEMBL6492339 | 0.71 | BRD4 (0.46) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |