Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127136 | 0.93 | SLC29A1 (0.37) | DHFRHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL7126031 | 0.92 | SLC29A1 (0.39) | DHFRHSP90AA1HSP90AB1SLC29A1CYP2C19 | |
| SCHEMBL7128310 | 0.91 | SLC29A1 (0.41) | DHFRHSP90AA1HSP90AB1SLC29A1CYP2C19 | |
| SCHEMBL7131165 | 0.91 | HSP90AA1 (0.36) | DHFRHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL7118004 | 0.91 | CYP1A2 (0.35) | DHFRHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL7122263 | 0.90 | NSD3 (0.40) | DHFRHSP90AA1HSP90AB1ADORA2ASLC29A1 | |
| SCHEMBL7127268 | 0.88 | CYP2C19 (0.35) | SLC29A1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7118005 | 0.88 | CYP1A2 (0.41) | ADORA2ASLC29A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL7129054 | 0.85 | DHFR (0.39) | DHFRHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL7126789 | 0.85 | DHFR (0.42) | DHFRHSP90AA1HSP90AB1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109498-A1 | Antiviral agent for drug-resistant virus | MITSUBISHI PHARMA CORPORATION (JP) | 2003-06-12 | — | — | US | claimed |
| US-20030109498-A1 | Antiviral agent for drug-resistant virus | MITSUBISHI PHARMA CORPORATION (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-0785208-B1 | Phosphonate nucleotide compounds | MITSUBISHI CHEM CORP (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0785208-A1 | Phosphonate nucleotide compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109498-A1 | Antiviral agent for drug-resistant virus | TPMT, MTAP, TYMP | DHFR 335/4885HSP90AA1 3605/4885HSP90AB1 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.