SCHEMBL7126019

SCHEMBL7126019

O=c1nc2nc[nH]n2c(O)c1Br

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 18/20 0.44
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9598677 0.64 KDM5B (0.48) KDM5BKDM4E
SCHEMBL17784391 0.58 KDM5B (0.43) KDM5B
SCHEMBL7014760 0.57 KDM5B (0.50) KDM5B
SCHEMBL16432965 0.56 KDM5B (0.49) KDM5B
SCHEMBL2271041 0.52
SCHEMBL2270862 0.46
SCHEMBL1771093 0.46
SCHEMBL10521646 0.40
SCHEMBL38666299 0.39
SCHEMBL20683223 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003039259-A1 FUNGICIDES SYNGENTA LIMITED (GB) 2003-05-15 WO disclosed