Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752263 | 0.89 | DRD4 (0.48) | DRD4MCHR1PIN1RXFP1ALDH1A1 | |
| SCHEMBL5751220 | 0.89 | DRD4 (0.48) | DRD4MCHR1PIN1RXFP1ALDH1A1 | |
| SCHEMBL5751363 | 0.86 | DRD4 (0.51) | DRD4MCHR1PIN1RXFP1ALDH1A1 | |
| SCHEMBL5750142 | 0.85 | DRD4 (0.40) | DRD4MCHR1UTS2RPIN1BACE1 | |
| SCHEMBL5753845 | 0.83 | DRD4 (0.41) | DRD4MCHR1TRPV1PTGER4PTGDR | |
| SCHEMBL5753159 | 0.82 | DRD4 (0.39) | DRD4MCHR1UTS2RPIN1PTGER4 | |
| SCHEMBL5752112 | 0.82 | DRD4 (0.50) | DRD4MCHR1PIN1RXFP1BACE1 | |
| SCHEMBL5752865 | 0.81 | PIN1 (0.57) | DRD4MCHR1PIN1HDAC8HDAC3 | |
| SCHEMBL5753785 | 0.81 | HDAC8 (0.46) | ALDH1A1LMNABACE1CNR2CCR3 | |
| SCHEMBL5754521 | 0.80 | MCHR1 (0.48) | DRD4MCHR1BACE1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |