Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807276 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL14238765 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL71270 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL14819793 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL15357515 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL10046211 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL14998225 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL13165198 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL71129 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL22402582 | 0.96 | GLP1R (0.67) | GLP1RNOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129343-B2 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2012-03-06 | — | — | US | disclosed |
| US-8129343-B2 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2012-03-06 | — | — | US | disclosed |
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156478-A1 | Acylated GLP-1 Compounds | GLP1R, GIPR, GCGR | GLP1R 1/4885NOD1 1340/4885FOLH1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.