Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807276 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL14238765 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL71270 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL14819793 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL15357515 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL14998225 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL13165198 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL71264 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL71129 | 1.00 | GLP1R (0.62) | GLP1RNOD1FOLH1HPGDHTT | |
| SCHEMBL22402582 | 0.96 | GLP1R (0.67) | GLP1RNOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670261-B2 | Functionalized exendin-4 derivatives | SANOFI (FR) | 2017-06-06 | — | — | US | disclosed |
| US-9556250-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2017-01-31 | — | — | US | disclosed |
| US-9486505-B2 | Glucagon analogues | NOVO NORDISK A/S (DK) | 2016-11-08 | — | — | US | disclosed |
| US-20140213513-A1 | Exendin-4 Derivatives as dual GLP1/GIP or trigonal GLP1/GIP/Glucagon Agonists | SANOFI (FR) | 2014-07-31 | — | — | US | disclosed |
| US-20140206609-A1 | Functionalized Exendin-4 Derivatives | SANOFI (FR) | 2014-07-24 | — | — | US | disclosed |
| US-20130288958-A1 | Novel Glucagon Analogues | NOVO NORDISK AS (DK) | 2013-10-31 | — | — | US | disclosed |
| US-20120035099-A1 | FGF21 ANALOGUES AND DERIVATIVES | NOVO NORDISK A/S (DK) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130288958-A1 | Novel Glucagon Analogues | GLP1R, GCG, GCGR | GLP1R 1/4885NOD1 1939/4885FOLH1 352/4885 |
| US-20140206609-A1 | Functionalized Exendin-4 Derivatives | GLP1R, NPY4R, MC4R | GLP1R 1/4885NOD1 1330/4885FOLH1 1324/4885 |
| US-20140213513-A1 | Exendin-4 Derivatives as dual GLP1/GIP or trigonal GLP1/GIP/Glucagon Agonists | GLP1R, GIPR, GCGR | GLP1R 1/4885NOD1 1234/4885FOLH1 1237/4885 |
| US-20120035099-A1 | FGF21 ANALOGUES AND DERIVATIVES | FGF1, FGFR1, FGF2 | GLP1R 11/4885NOD1 1732/4885FOLH1 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.