SCHEMBL7126483

SCHEMBL7126483

O=C(O)Cc1c(Cl)n(Cl)c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 3/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
EGFR P00533 1/20 0.51
LCK P06239 1/20 0.49
PRKACA P17612 1/20 0.49
CSNK2A2 P19784 1/20 0.49
PRKACG P22612 1/20 0.49
PRKACB P22694 1/20 0.49
GSK3B P49841 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
DYRK1A Q13627 1/20 0.49
CSNK2A3 Q8NEV1 1/20 0.49
PTGDR2 Q9Y5Y4 3/20 0.47
AKR1B1 P15121 2/20 0.46
FOLH1 Q04609 1/20 0.45
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756204 0.78 AKR1B1 (0.56) ABCB1PTGS1PTGS2PTGDR2AKR1B1
SCHEMBL23120097 0.77 SLC7A5 (0.50) PTGS1PTGS2KDM4EALDH1A1LMNA
SCHEMBL28738543 0.77 SLC7A5 (0.50) PTGS1PTGS2KDM4EALDH1A1LMNA
SCHEMBL30130273 0.71 KDM4E (0.59) PTGS1EGFRLCKPRKACACSNK2A2
SCHEMBL7826233 0.71 KDM4E (0.59) PTGS1EGFRLCKPRKACACSNK2A2
SCHEMBL10494824 0.71 EGFR (0.38) EGFRKDM4EALDH1A1HSD17B10LMNA
SCHEMBL10494819 0.71 CHRM2 (0.53) KDM4EALDH1A1
SCHEMBL11194435 0.71 TDP1 (0.51) ABCB1PTGS1PTGS2EGFRAKR1B1
SCHEMBL4881610 0.71 FOLH1 (0.55) ABCB1EGFRPTGDR2FOLH1KDM4E
SCHEMBL2237296 0.70 ABCB1 (1.00) ABCB1PTGS1PTGS2PTGDR2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271032-B1 GROWING THE PLANT IN THE PRESENCE OF A GROWTH-ENHANCING FORMULATION COMPRISING 5-BROMOINDOLE-3-ACETIC ACID, ITS SALT, ESTER OR AMIDE DERIVATIVE INVITROGEN CORPORATION 2001-08-07 US claimed
US-20030083202-A1 Roots-inducing agent of plants and its treatment method KATAYAMA, MASATO (JP) 2003-05-01 US disclosed
CN-1401231-A Plant rooting promoter and treatment method thereof IND TECH COMPLEX INST (JP) 2003-03-12 CN disclosed
EP-0256128-B1 INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-11-06 EP disclosed
US-4806143-A Indoleacetic acid derivatives and application thereof as plant growth regulators NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-02-21 US disclosed
EP-0256128-A1 INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030083202-A1 Roots-inducing agent of plants and its treatment method CROCC, PMAIP1, CYC1 ABCB1 2067/4885PTGS1 31/4885PTGS2 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.