Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 16/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Retinal SCHEMBL1434925 | 0.88 | STING1 (0.62) | STING1 | |
| Adenosine Phosphate SCHEMBL10754693 | 0.81 | P2RY1 (0.58) | — | |
| Cyclic Adenosine Monophosphate SCHEMBL23829673 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| SCHEMBL22434642 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| Cyclic Adenosine Monophosphate SCHEMBL1264 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| Cyclic Adenosine Monophosphate SCHEMBL23829591 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| Cyclic Adenosine Monophosphate SCHEMBL23829670 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| Cyclic Adenosine Monophosphate SCHEMBL23829653 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| Cyclic Adenosine Monophosphate SCHEMBL20912149 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM | |
| Cyclic Adenosine Monophosphate SCHEMBL23829820 | 0.78 | STING1 (1.00) | STING1LMNARAPGEF3GMNNBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030118506-A1 | Gene encoding the rat dopamine D4 receptor | WASHINGTON UNIVERSITY | 2003-06-26 | — | — | US | disclosed |
| US-6486310-B1 | Gene encoding the rat dopamine D4 receptor | WASHINGTON UNIVERSITY | 2002-11-26 | — | — | US | disclosed |
| US-6121015-A | DRUG SCREENING BY TRANSFECTING CELLS WITH NUCLEIC ACID, EXPRESSING RECEPTOR, SELECTING COMPOUNDS BINDING TO RECEPTOR, COMPARING BINDING TO OTHER RECEPTORS, CHOOSING COMPOUNDS WHICH HAVE LOWER AFFINITY TO OTHER RECEPTORS | WASHINGTON UNIVERSITY (US) | 2000-09-19 | — | — | US | disclosed |