Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.62 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclic Adenosine Monophosphate SCHEMBL7126687 | 0.88 | STING1 (0.60) | STING1 | |
| SCHEMBL14980248 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL12671632 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL12634565 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL17974376 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL24467522 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL18737202 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL21470181 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL21498373 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A | |
| SCHEMBL17325408 | 0.79 | STING1 (1.00) | STING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773638-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF VISION LOSS THROUGH GENERATION OF ROD PHOTORECEPTORS FROM MÜLLER GLIAL CELLS | Icahn School of Medicine at Mount Sinai (US) | 2021-02-17 | — | — | EP | claimed |
| WO-2019195717-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF VISION LOSS THROUGH GENERATION OF ROD PHOTORECEPTORS FROM MÜLLER GLIAL CELLS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2019-10-10 | — | — | WO | claimed |
| EP-0513203-A4 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | — | 1992-12-02 | — | — | EP | claimed |
| EP-0513203-A1 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1992-11-19 | — | — | EP | claimed |
| WO-1991011532-A1 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-08-08 | — | — | WO | claimed |
| EP-3773638-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF VISION LOSS THROUGH GENERATION OF ROD PHOTORECEPTORS FROM MÜLLER GLIAL CELLS | Icahn School of Medicine at Mount Sinai (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195717-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF VISION LOSS THROUGH GENERATION OF ROD PHOTORECEPTORS FROM MÜLLER GLIAL CELLS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2019-10-10 | — | — | WO | disclosed |
| US-8334369-B2 | Mutations in human UBIAD1 | GENOME ATLANTIC (CA) | 2012-12-18 | — | — | US | disclosed |
| EP-1944305-B1 | Quinoline derivatives as phosphodiesterase inhibitors | GLAXO GROUP LTD (GB) | 2011-10-19 | — | — | EP | disclosed |
| US-8003342-B1 | Method for identifying farnesyl transferase inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003663-B2 | N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}-4-({8-[(2-hydroxyethyl)(methyl)amino]octanoyl}amino)benzamide; phosphodiesterase inhibitor; antiinflammatory, antiallergenic agent; chronic obstructive pulmonary disease (COPD), asthma, or rhinitis | GLAXO GROUP LIMITED (GB) | 2011-08-23 | — | — | US | disclosed |
| EP-2046787-B1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | GLAXO GROUP LTD (GB) | 2011-04-06 | — | — | EP | disclosed |
| EP-0656903-A1 | METHODS AND COMPOSITIONS FOR THE IDENTIFICATION, CHARACTERIZATION, AND INHIBITION OF FARNESYLTRANSFERASE | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5264565-A | Nucleic acid encoding the D2 /Ml chimeric receptor | AFFYMAX TECHNOLOGIES, N.V. (NL) | 1993-11-23 | — | — | US | disclosed |
| US-5262529-A | Probe of single-stranded oligonucleotide (DNA) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1993-11-16 | — | — | US | disclosed |
| US-5225546-A | Diagnosis of hereditary retinal degenerative disease | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1993-07-06 | — | — | US | disclosed |
| WO-1993012134-A1 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1993-06-24 | — | — | WO | disclosed |
| EP-0513203-A4 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | — | 1992-12-02 | — | — | EP | disclosed |
| EP-0513203-A1 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1991011532-A1 | DIAGNOSIS OF HEREDITARY RETINAL DEGENERATIVE DISEASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-08-08 | — | — | WO | disclosed |