Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386003 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL9455923 | 0.81 | GRIN2D (0.37) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL2110437 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL190969 | 0.81 | GRIN2D (0.37) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL2113357 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL191847 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL13728842 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL13788797 | 0.78 | TDP1 (0.39) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL29880665 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL9702186 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRSMN1; SMN2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114184699-B | Method for determining potential genotoxic impurities in esomeprazole sodium by liquid chromatography-mass spectrometry | 北京悦康科创医药科技股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-216727160-U | Volumetric flask for preparing 2,3, 5-trimethyl-4-nitropyridine-N-oxide | 济南泺合医药技术有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-114184699-A | Method for determining potential genotoxic impurities in esomeprazole sodium by liquid chromatography-mass spectrometry | 北京悦康科创医药科技股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114044752-A | Production method of omeprazole drug intermediate 2-chloromethyl-3, 5-dimethyl-4-methoxypyridine hydrochloride | 上海卓鼎生物技术有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-111943883-A | Production process of Orimei chloride | 抚州三和医药化工有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-111077249-A | Method for detecting 4-nitro-2, 3, 5-trimethylpyridine-N-oxide by UPLC-MS/MS | 江苏乾元生物科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-109836380-A | A kind of preparation method of 4- nitro -2,3,5- trimethylpyridine-N- oxide | 盘锦研峰科技有限公司 | 2019-06-04 | — | — | CN | claimed |
| US-6303787-B1 | STARTING FROM 4-NITRO-2,3,5-TRIMETHYLPYRIDINE-N-OXIDE AND5-METHOXY-2-MERCAPTO BENZIMIDAZOLE | NATCO PHARMA LIMITED (IN) | 2001-10-16 | — | — | US | claimed |
| CN-117865882-A | Preparation method of 4-nitropyridine-N-oxide | 滁州学院 | 2024-04-12 | — | — | CN | disclosed |
| CN-110317164-B | Preparation method of omeprazole intermediate | 抚州三和医药化工有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-216727160-U | Volumetric flask for preparing 2,3, 5-trimethyl-4-nitropyridine-N-oxide | 济南泺合医药技术有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-216727160-U | Volumetric flask for preparing 2,3, 5-trimethyl-4-nitropyridine-N-oxide | 济南泺合医药技术有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-216727160-U | Volumetric flask for preparing 2,3, 5-trimethyl-4-nitropyridine-N-oxide | 济南泺合医药技术有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114044752-A | Production method of omeprazole drug intermediate 2-chloromethyl-3, 5-dimethyl-4-methoxypyridine hydrochloride | 上海卓鼎生物技术有限公司 | 2022-02-15 | — | — | CN | disclosed |
| US-4766133-A | ANTIULCER AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1988-08-23 | — | — | US | disclosed |
| US-4634710-A | ANTIULCER, ANTISECRETORY | HOFFMANN-LA ROCHE INC. (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0178438-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |
| US-4560693-A | ANTISECRETORY, ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-12-24 | — | — | US | disclosed |
| US-4555518-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-11-26 | — | — | US | disclosed |
| US-4472409-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-18 | — | — | US | disclosed |