Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 7/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177829 | 0.81 | CA12 (0.57) | POLBCA12CA9CA1CA2 | |
| SCHEMBL4385793 | 0.81 | CA12 (0.65) | POLBCA12CA9CA1CA2 | |
| SCHEMBL31415605 | 0.81 | CA12 (0.65) | POLBCA12CA9CA1CA2 | |
| SCHEMBL5816621 | 0.79 | MAOB (0.61) | POLBCA12CA9CA1CA2 | |
| SCHEMBL5190662 | 0.79 | POLB (1.00) | POLBCA12CA9CA1CA2 | |
| SCHEMBL8810276 | 0.79 | CA12 (1.00) | POLBCA12CA9CA1CA2 | |
| SCHEMBL1369655 | 0.78 | MAOB (0.81) | POLBCA12CA9CA1CA2 | |
| SCHEMBL1997538 | 0.78 | MAOB (0.59) | POLBCA12CA9CA1CA2 | |
| SCHEMBL831487 | 0.78 | CA12 (0.79) | POLBCA12CA9CA1CA2 | |
| SCHEMBL3281919 | 0.78 | MAOB (0.80) | POLBCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003252869-A | METHOD FOR PRODUCING 3-AMINO-6-NITROCOUMARIN | SUMITOMO SEIKA CHEM CO LTD | 2003-09-10 | — | — | JP | disclosed |
| EP-0553248-A1 | NOVEL 5-IODO-6-AMINO-1,2-BENZOPYRONES AND THEIR ANALOGS USEFUL AS CYTOSTATIC AND ANTIVIRAL AGENTS. | UNIV CALIFORNIA (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0494231-A4 | 6-AMINO-1,2-BENZOPYRONES USEFUL FOR TREATMENT OF VIRAL DISEASES | — | 1992-09-16 | — | — | EP | disclosed |
| EP-0494231-A1 | 6-AMINO-1,2-BENZOPYRONES USEFUL FOR TREATMENT OF VIRAL DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-07-15 | — | — | EP | disclosed |
| WO-1992006687-A1 | NOVEL 5-IODO-6-AMINO-1,2-BENZOPYRONES AND THEIR ANALOGS USEFUL AS CYTOSTATIC AND ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-04-30 | — | — | WO | disclosed |
| WO-1991004663-A1 | 6-AMINO-1,2-BENZOPYRONES USEFUL FOR TREATMENT OF VIRAL DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-04-18 | — | — | WO | disclosed |
| US-4287126-A | (2-Oxo-2H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives | WARNER-LAMBERT COMPANY (US) | 1981-09-01 | — | — | US | disclosed |